The technique is a relatively simple one. First, viable tissue is obtained from a source plant. This material is called an explant. Next, a small cut is made in the explant. New cells form on the surface of this cut in an attempt to heal the wound. This colorless mass of cells is called a callus. The slowly dividing cells of a callus are undifferentiated cells that lack the characteristics of normal plant cells. They are essentially unprogrammed and full of potential.
With this technology, it is theoretically possible to propagate any plant cell in a liquid culture, opening up a whole new realm of possibilities. This fact started scientists thinking—what would happen if an extract of genetically long-lived plant stem cell tissue was applied to human skin?
Comparing Apples to Apples
Today, apples are cultivated primarily to enhance their appearance and flavor. But before the rise of refrigeration, an apple’s ability to stay fresh for a long time was its most sought-after characteristic.
For this reason, a special variety of apple was cultivated in the middle of the 18th century that could be stored for a greatly extended period of time. In essence, it was the genetically modified, longer-living stem cells of this tannin-rich variety of apple, called the Uttwiler Spatlauber apple, which were responsible for its unique storage longevity.
In a certain isolated area of rural Switzerland, a few of these hardy apple trees still survive today. Scientists obtained an explant from the leaf of one of these trees to produce a special anti-aging stem cell extract.
The Amazing Results
In order to test the theory that this unique plant extract would produce anti-aging effects, scientists at Mibelle Biochemistry first obtained human stem cells from the blood of an umbilical cord. Their first in-house study on cell viability showed that, at a concentration of only 0.1%, an extract of Uttwiler Spatlauber stem cells stimulated the proliferation of human stem cells by an astounding 80%! 5
In a second experiment, these scientists irradiated the umbilical cord blood stem cells with uv light. Nearly 50% of the stem cells cultured in growth medium alone died, but the cells grown in the culture containing the special apple extract showed only a small decrease in the number of living cells.5
Another in vitro experiment conducted by the scientists involved fibroblast cells. These are the most common of all cells in the connective tissue of the skin. They manufacture the collagen, glycosaminoglycans, reticular and elastic fibers, and glycoproteins that